Evidence Tiers Explained

FDA Approved

The compound has an approved medical use in the United States. This does not mean every off-label claim is validated, and it does not turn AtlasED into medical advice.

Phase 3 / late-stage clinical

Large human trials exist or are underway. This is strong signal, but readers should still look at population, endpoint, dose, comparator, adverse events, and publication quality.

Phase 1-2 / early clinical

Human data exists, but the evidence base may be smaller, narrower, or preliminary. Promising does not mean proven.

Preclinical

Evidence is mostly animal, cell, mechanistic, or early lab work. It can explain why researchers are interested, but it should not be treated as proof of human benefit.

Community signal

• Useful for: patterns, questions, side-effect reports, and practical observations.
• Not useful for: clinical proof, safety guarantees, or universal dosing claims.